A cura di MIUR - Direzione Generale per il coordinamento la promozione e la valorizzazione della ricerca

Understanding Cancer. The way to cure it.


Founded in 1998 by the Italian Foundation for Cancer Research (FIRC), the FIRC Institute of Molecular Oncology (IFOM) is a cancer research institute focused on the study of cancer formation and development at molecular level, with a view to a rapid transfer of results from bench to bedside.


“Understanding cancer. The way to cure it”. This is the founding principle of research made at IFOM: a centre focusing on the study of the molecular mechanisms underlying tumors formation and development. In this scientific field, knowledge is the ultimate condition for medical care.

Researchers from all over the world pursue this one and only aim, in a multidisciplinary way and in different research fields: from molecular and cell biology to structural and computational biology, from genomics to proteomics, from molecular diagnostics to pharmacogenomics, from immunology to metabolomics.

IFOM, MilanoIFOM, MilanoCooperating with biomedical organizations as well as local institutions on one side, developing a network of strategic alliances with the most competitive international research centres on the other: this is deeply embedded in IFOM DNA. Doing research together is meant to undertake joint projects aiming at accelerating the acquisition of new knowledge and its application.

IFOM has established a network of partnerships with cutting-edge scientific organizations around the world that go beyond traditional project-based collaborations. Complementary strategies, shared scientific objectives and integration of resources are the key elements at the heart of these international ventures.

The Institute has its laboratories in three geographical areas:

  • In Milan (Italy) IFOM is located close to the city centre within the Campus IFOM-IEO in a former industrial area of 12.000 sqm completely renovated and equipped with cutting edge technologies. The Campus is a location shared with the Department of Experimental Oncology of the European Institute of Oncology and other research organizations such as TT-Factor, the European School of Molecular Medicine, Cogentech and the Italian Institute of Technology. Since its establishment IFOM has been collaborating with important local biomedical institutions through agreements aiming at creating synergies in terms of resources and technologies. The research groups hosted in Milan headqquarter are:

Genomics of Cancer and Targeted Therapies
Transcriptional Regulation in Development and Cancer  
DNA Repair
Genetics of B Cells and Lymphomas  
Quantitative Biology of Cell Division
DNA Metabolism
DNA Damage Response and Cellular Senescence
New strategies to inhibit tumor angiogenesis
Cellular Logistics in Cancer
Genome Integrity  
Intracellular Transport and Tumorigenesis
DNA Editing in Immunity and Epigenetics
Ubiquitin and Signal Transduction
Mechanisms of Tumor Cell Migration
Cell Matrix Signaling
Membrane Trafficking and Tissue Architecture

  • Singapore is nowadays a well-established hub for biomedical research with a vibrant research community and increasing investments in innovation that lead to high quality research. In Singapore the Joint Research Lab between IFOM and A*STAR (Agency for Science, Technology and Research) aims at identifying new therapeutical approaches against cancer and it leverages the combined knowledge and technological expertise of the two agencies to accelerate the transfer of scientific findings from the laboratory to clinical practice. The research programme hosted in IFOM Joint Research Lab in Singapore is: 

New Molecular Targets for Anticancer Therapies

  • India represents one of the most promising incubators of scientific and technological development in the world. Starting from 2012 IFOM has established agreements of collaboration with the most innovative Indian research institutes – as for example NCBS (National Centre for Biological Sciences) e inSTEM (Institute for Stem Cell Biology and Regenerative Medicine) - and integrate the partners' skills in the cutting-edge science area of regenerative medicine. The IFOM Joint Research Lab in Bangalore (India)  studies the molecular processes of tissue regeneration from adult stem cells and the application of this knowledge in cancer research, diabetes and atopic dermatitis, as well as the repair of damaged organs that have limited regenerative abilities, such as the heart and brain. The research programme hosted in IFOM Joint Research Lab in Bangalore is:

Stem Cells and Tissue Regeneration

IFOM-ASTAR - IFOM-A*STAR Joint Research Lab
IFOM-INSTEM - IFOM-inSTEM Joint Research Lab
Publication date 06/27/2013